Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152286
tested applications
ELISA
Description
Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MCHR1 concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Melanin Concentrating Hormone Receptor 1 (MCHR1)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Melanin Concentrating Hormone Receptor 1 (MCHR1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.11 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q99705 |
| Alias | MCHR1,GPR24,MCH-1R,MCH1R,SLC-1,SLC1,G protein-coupled receptor 24,MCH receptor 1,somatostatin receptor-like protein |
| Background | Elisa kits for MCHR1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
MCHR1 is a G protein-coupled receptor (GPCR) activated by melanin-concentrating hormone (MCH), a neuropeptide involved in energy homeostasis, feeding behavior, and emotional regulation. MCHR1 is widely expressed in the central nervous system (CNS), particularly in regions such as the hypothalamus, hippocampus, and cerebral cortex, where it mediates the effects of MCH on appetite stimulation, energy storage, and mood regulation. MCHR1 primarily signals through Gi/o proteins, inhibiting adenylate cyclase activity and reducing cyclic AMP (cAMP) levels, while also activating MAPK and calcium signaling pathways. Dysregulation of MCHR1 is associated with obesity, metabolic disorders, and psychiatric conditions, such as depression and anxiety, due to its role in regulating energy balance and mood. Pharmacological antagonists of MCHR1 are being developed as potential treatments for obesity by suppressing appetite and reducing energy storage, while agonists may have applications in mood disorders. MCHR1’s involvement in feeding, energy metabolism, and emotional regulation highlights its therapeutic significance in metabolic and neurological disorders.
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