Human MCHR1 (Melanin-concentRating hormone receptor 1) ELISA Kit
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name
Human MCHR1 (Melanin-concentRating hormone receptor 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1306
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q99705 |
| Alias | MCHR1,GPR24,MCH-1R,MCH1R,SLC-1,SLC1,G protein-coupled receptor 24,MCH receptor 1,somatostatin receptor-like protein |
| Background | Elisa kits for MCHR1 |
| Status | RUO |
MCHR1 is a G protein-coupled receptor (GPCR) activated by melanin-concentrating hormone (MCH), a neuropeptide involved in energy homeostasis, feeding behavior, and emotional regulation. MCHR1 is widely expressed in the central nervous system (CNS), particularly in regions such as the hypothalamus, hippocampus, and cerebral cortex, where it mediates the effects of MCH on appetite stimulation, energy storage, and mood regulation. MCHR1 primarily signals through Gi/o proteins, inhibiting adenylate cyclase activity and reducing cyclic AMP (cAMP) levels, while also activating MAPK and calcium signaling pathways. Dysregulation of MCHR1 is associated with obesity, metabolic disorders, and psychiatric conditions, such as depression and anxiety, due to its role in regulating energy balance and mood. Pharmacological antagonists of MCHR1 are being developed as potential treatments for obesity by suppressing appetite and reducing energy storage, while agonists may have applications in mood disorders. MCHR1’s involvement in feeding, energy metabolism, and emotional regulation highlights its therapeutic significance in metabolic and neurological disorders.
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