Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit
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935106861
info@markelab.com
Precio
585€ (96 tests)
Elisa kits for MCHR1
proveedor
Abbexareference
abx055009Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Melanin Concenting Hormone Receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
MCHR1 is a G protein-coupled receptor (GPCR) activated by melanin-concentrating hormone (MCH), a neuropeptide involved in energy homeostasis, feeding behavior, and emotional regulation. MCHR1 is widely expressed in the central nervous system (CNS), particularly in regions such as the hypothalamus, hippocampus, and cerebral cortex, where it mediates the effects of MCH on appetite stimulation, energy storage, and mood regulation. MCHR1 primarily signals through Gi/o proteins, inhibiting adenylate cyclase activity and reducing cyclic AMP (cAMP) levels, while also activating MAPK and calcium signaling pathways. Dysregulation of MCHR1 is associated with obesity, metabolic disorders, and psychiatric conditions, such as depression and anxiety, due to its role in regulating energy balance and mood. Pharmacological antagonists of MCHR1 are being developed as potential treatments for obesity by suppressing appetite and reducing energy storage, while agonists may have applications in mood disorders. MCHR1’s involvement in feeding, energy metabolism, and emotional regulation highlights its therapeutic significance in metabolic and neurological disorders.
Características del producto
category
ELISA Kits
immunogen target
Melanin Concentrating Hormone Receptor 1 (MCHR1)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
MCHR1,GPR24,MCH-1R,MCH1R,SLC-1,SLC1,G protein-coupled receptor 24,MCH receptor 1,somatostatin receptor-like protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MCHR1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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