Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit

Este producto es parte de MCHR - Melanin Concentrating Hormone Receptor
Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

585€ (96 tests)

Elisa kits for MCHR1

proveedor

Abbexa

reference

abx055009

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Melanin Concentrating Hormone Receptor 1 (MCHR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Melanin Concenting Hormone Receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

MCHR1 is a G protein-coupled receptor (GPCR) activated by melanin-concentrating hormone (MCH), a neuropeptide involved in energy homeostasis, feeding behavior, and emotional regulation. MCHR1 is widely expressed in the central nervous system (CNS), particularly in regions such as the hypothalamus, hippocampus, and cerebral cortex, where it mediates the effects of MCH on appetite stimulation, energy storage, and mood regulation. MCHR1 primarily signals through Gi/o proteins, inhibiting adenylate cyclase activity and reducing cyclic AMP (cAMP) levels, while also activating MAPK and calcium signaling pathways. Dysregulation of MCHR1 is associated with obesity, metabolic disorders, and psychiatric conditions, such as depression and anxiety, due to its role in regulating energy balance and mood. Pharmacological antagonists of MCHR1 are being developed as potential treatments for obesity by suppressing appetite and reducing energy storage, while agonists may have applications in mood disorders. MCHR1’s involvement in feeding, energy metabolism, and emotional regulation highlights its therapeutic significance in metabolic and neurological disorders.

Características del producto

category

ELISA Kits


immunogen target

Melanin Concentrating Hormone Receptor 1 (MCHR1)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

MCHR1,GPR24,MCH-1R,MCH1R,SLC-1,SLC1,G protein-coupled receptor 24,MCH receptor 1,somatostatin receptor-like protein


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

MCHR1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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