Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx533644
tested applications
ELISA
Description
Human Mas-related G-protein coupled receptor member X2 (MRGPRX2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Mas-related G-protein coupled receptor member X2 (MRGPRX2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | MAS Related GPR Member X2 (MRGPRX2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | < 0.65 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96LB1 |
| Gene ID | 117194 |
| OMIM | 607228 |
| Alias | MRGPRX2,Mrgprb10,MRGX2,MGRG3 |
| Background | Elisa kits for MRGPRX2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
MRGPRX2 is another receptor in the MAS-related GPR family, which is involved in immune and sensory functions. It is primarily expressed in mast cells and sensory neurons, where it contributes to the regulation of allergic reactions and inflammatory responses. MRGPRX2 is activated by endogenous peptides, including substance P, and plays a significant role in mediating the release of histamine from mast cells, leading to allergic symptoms such as itching, swelling, and redness. Additionally, MRGPRX2 has been implicated in pain signaling and neurogenic inflammation. This receptor’s involvement in allergic responses and its ability to modulate mast cell activation makes it a key player in conditions such as asthma, rhinitis, and other allergic disorders. Targeting MRGPRX2 with antagonists offers therapeutic potential for treating allergic conditions and managing symptoms related to mast cell activation.
Related Products
Human MRGPRX2 (Mas-related G-protein coupled receptor member X2) ELISA Kit
Ver Producto
Mas-Related G-Protein Coupled Receptor Member X2 (MRGPRX2) Antibody (HRP)
MRGPRX2 Antibody (HRP) is a Rabbit Polyclonal against MRGPRX2 conjugated to HRP.
Ver Producto
Mas-Related G-Protein Coupled Receptor Member X2 (MRGPRX2) Antibody (FITC)
MRGPRX2 Antibody (FITC) is a Rabbit Polyclonal against MRGPRX2 conjugated to FITC.
Ver Producto