Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for MRGPRX2
proveedor
Abbexareference
abx384944Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
This product is currently under production. The lead time for this product may be several months. Please contact us at
Background
MRGPRX2 is another receptor in the MAS-related GPR family, which is involved in immune and sensory functions. It is primarily expressed in mast cells and sensory neurons, where it contributes to the regulation of allergic reactions and inflammatory responses. MRGPRX2 is activated by endogenous peptides, including substance P, and plays a significant role in mediating the release of histamine from mast cells, leading to allergic symptoms such as itching, swelling, and redness. Additionally, MRGPRX2 has been implicated in pain signaling and neurogenic inflammation. This receptor’s involvement in allergic responses and its ability to modulate mast cell activation makes it a key player in conditions such as asthma, rhinitis, and other allergic disorders. Targeting MRGPRX2 with antagonists offers therapeutic potential for treating allergic conditions and managing symptoms related to mast cell activation.
Características del producto
category
ELISA Kits
immunogen target
MAS Related GPR Member X2 (MRGPRX2)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
MRGPRX2,Mrgprb10,MRGX2,MGRG3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MRGPRX2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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