Human Lysophosphatidic Acid Receptor 4 (LPAR4) ELISA Kit

Este producto es parte de LPAR - Lysophosphatidic Acid Receptor
Human Lysophosphatidic Acid Receptor 4 (LPAR4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LPAR4

proveedor

Abbexa

reference

abx253944

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Lysophosphatidic Acid Receptor 4 (LPAR4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Lysophosphatidic acid receptor 4 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

LPAR4 is a G protein-coupled receptor for lysophosphatidic acid (LPA) that preferentially couples to G12/13 and Gq proteins, influencing cytoskeletal organization, calcium signaling, and cell migration. LPAR4 is expressed in hematopoietic cells, endothelial cells, and certain epithelial tissues, where it regulates cell adhesion, proliferation, and vascular development. Unlike other LPA receptors, LPAR4 has been implicated in blood vessel stability and lymphocyte trafficking, playing a role in vascular homeostasis and immune cell regulation. LPAR4 activation contributes to endothelial barrier function and vascular remodeling, making it relevant in conditions such as vascular inflammation and atherosclerosis. In cancer, LPAR4’s role is less well characterized compared to other LPA receptors, but it has been linked to cell migration and metastasis in certain malignancies. Dysregulation of LPAR4 signaling is associated with vascular disorders and immune dysfunction. Targeting LPAR4 offers therapeutic potential for vascular diseases, immune modulation, and cancer progression, highlighting its emerging role in LPA-mediated signaling pathways.

Características del producto

category

ELISA Kits


immunogen target

Lysophosphatidic Acid Receptor 4 (LPAR4)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.12 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

LPAR4,GPR23,LPA4,P2RY9,P2Y5-LIKE,P2Y9,P2Y5-like receptor,G protein-coupled receptor 23,LPA receptor 4,P2Y,purinoceptor 9,Purinergic receptor 9


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LPAR4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human LPAR4(Lysophosphatidic acid receptor 4) ELISA Kit

Human LPAR4(Lysophosphatidic acid receptor 4) ELISA Kit

proveedor

FineTest

reference

EH0990

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse Lpar4(Lysophosphatidic acid receptor 4) ELISA Kit

Mouse Lpar4(Lysophosphatidic acid receptor 4) ELISA Kit

proveedor

FineTest

reference

EM0427

reactivity

mouse

status

RUO

Precio a consultar

Ver más

anti- LPAR4 antibody

anti- LPAR4 antibody

proveedor

FineTest

reference

FNab04824

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Receptor for lysophosphatidic acid(LPA), a mediator of diverse cellular activities. Transduces a signal by increasing th...

Precio a consultar

Ver más