Human LGR4 (Leucine-rich repeat-containing G-protein coupled receptor 4) ELISA Kit
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Name
Human LGR4 (Leucine-rich repeat-containing G-protein coupled receptor 4) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1317
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 78.125-5000pg/ml |
| Sensitivity | 46.875pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9BXB1 |
| Alias | LGR4,GPR48,leucine-rich repeat-containing G protein-coupled receptor 4,leucine-rich repeat containing G protein-coupled receptor 4,DPSL,BNMD17 |
| Background | Elisa kits for LGR4 |
| Status | RUO |
Background
LGR4 is a member of the leucine-rich repeat-containing G protein-coupled receptor (LGR) family, which is activated by R-spondins, a group of proteins that regulate Wnt signaling. LGR4 plays a significant role in tissue development, differentiation, and homeostasis, particularly in the epithelial cells of various organs, including the gastrointestinal tract, kidney, and skin. It is involved in modulating Wnt/β-catenin signaling pathways, which are crucial for cell proliferation, stem cell maintenance, and differentiation. LGR4 is implicated in regulating processes such as embryogenesis, organogenesis, and tissue repair. Dysregulation of LGR4 signaling has been associated with conditions like cancer, particularly colorectal cancer, and disorders of tissue regeneration. LGR4 also plays a role in controlling blood pressure and fluid balance, with potential therapeutic applications in hypertension and renal diseases.
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