Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 (LILRB2) Protein

Este producto es parte de LILRB2 - leukocyte immunoglobulin like receptor B2
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 (LILRB2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168118
tested applications
WB, SDS-PAGE

Description

Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetLeukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 (LILRB2)
HostE. coli
OriginHuman
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 26.4 kDa Observed MW (SDS-PAGE): 26 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu53-Val255 Tag: N-terminal His tag
ExpressionRecombinant
Purity> 95%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ8N423
AliasLeukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,ILT4,LIR2,CD85D,ILT-4,LIR-2,MIR10,MIR-10,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,Monocyte/macrophage immunoglobulin-like receptor 10
BackgroundProtein LILRB2
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

LILRB2, also known as Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, ILT4 (Immunoglobulin-Like Transcript 4), or CD85d, is an inhibitory receptor expressed on immune cells, especially on myeloid cells, such as monocytes, macrophages, dendritic cells, and some granulocytes. It is part of the LILR family (leukocyte immunoglobulin-like receptors), which is encoded within the LRC (Leukocyte Receptor Complex) on chromosome 19q13.4. LILRB2 plays a major role in immune homeostasis by binding to MHC class I molecules and other ligands, leading to suppression of immune responses. This makes it a central player in controlling inflammation, self-tolerance, and response to chronic infections and tumors.

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