Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) ELISA Kit
715€ (96 tests)
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name
Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531542
tested applications
ELISA
Description
Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q3SXY7 |
| Gene ID | 345193 |
| Alias | CSNB1F,FIGLER4,Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 |
| Background | Elisa kits for LRIT3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRIT3 shares structural similarities with LRIT1, including its LRR and Ig-like domains, and plays a critical role in the proper functioning of retinal bipolar cells. LRIT3 is expressed specifically in the retina, where it is essential for the transmission of visual signals from photoreceptors to downstream neurons. Mutations in the LRIT3 gene are associated with autosomal recessive complete congenital stationary night blindness (cCSNB), which is characterized by impaired visual signal transmission despite normal photoreceptor activity. LRIT3 functions as a scaffold for synaptic proteins, ensuring proper synaptic architecture and signal fidelity within the retina. Its involvement in modulating postsynaptic responses underscores its significance in visual sensory processing.
Related Products
Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) ELISA Kit
Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) concentrations in tissue homogenates, cell lysates and other biological fluids.
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