Human Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) ELISA Kit

Este producto es parte de LRRFIP - LRR binding FLII interacting protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531585
tested applications
ELISA

Description

Human Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9Y608
Alias
LRR FLII-interacting protein 2,HUFI-2
Background
Elisa kits for LRRFIP2
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) shares structural and functional similarities with LRRFIP1 and participates in several critical cellular processes. LRRFIP2 has been identified as a modulator of innate immune responses, particularly in the NOD-like receptor signaling pathway, where it regulates the activation of inflammasomes and production of IL-1β. It also interacts with flightless I and contributes to cytoskeletal organization, playing a role in cell shape and motility. LRRFIP2's involvement in transcriptional regulation is mediated by its ability to bind DNA and influence gene expression. Emerging evidence suggests that LRRFIP2 may play a role in metabolic pathways and autophagy, although these functions require further investigation. Altered expression or mutations in LRRFIP2 have been linked to inflammatory diseases and metabolic disorders, underscoring its importance in maintaining cellular and systemic homeostasis.

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