Human Leucine-rich repeat-containing protein 45 (LRRC45) ELISA Kit

Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leucine-rich repeat-containing protein 45 (LRRC45) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531410
tested applications
ELISA

Description

Human Leucine-rich repeat-containing protein 45 (LRRC45) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 45 (LRRC45) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Leucine-rich repeat-containing protein 45 (LRRC45)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q96CN5
Alias
LRRC45
Background
Elisa Kits for: LRRC45
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

LRRC45 is a centrosomal protein implicated in microtubule organization and mitotic spindle formation during cell division its expression is highly enriched in proliferative tissues where it regulates centrosomal dynamics and ensures proper chromosome segregation studies suggest that LRRC45 interacts with key components of the centrosome and microtubule network to maintain cellular architecture and division fidelity dysregulation of LRRC45 has been associated with chromosomal instability and cancer progression particularly in aggressive tumors characterized by abnormal mitosis LRRC45 may also play a role in ciliogenesis by regulating microtubule anchoring and centrosome function ongoing research is focused on characterizing its interactions with centrosomal proteins and exploring its potential as a therapeutic target for cancers involving mitotic defects further understanding of its molecular function could provide insights into centrosome biology and its role in genomic stability

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