Human Leucine-rich repeat-containing protein 26 (LRRC26) ELISA Kit
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Descripción del producto
Human Leucine-rich repeat-containing protein 26 (LRRC26) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 26 (LRRC26) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Especificaciones del producto
| OMIM | 613505 |
| Alias | LRRC26, CAPC,Cytokeratin-associated protein in cancer,BK channel auxiliary gamma subunit LRRC26 |
| Assay Data | Quantitative |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Background | Elisa kits for LRRC26 |
| Category | ELISA Kits |
| Detection Method | Colorimetric |
| Dry Ice | No |
| Form | Lyophilized |
| Gene ID | 389816 |
| Immunogen Target | Leucine-rich repeat-containing protein 26 (LRRC26) |
| Name | Human Leucine-rich repeat-containing protein 26 (LRRC26) ELISA Kit |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Price | 715 |
| Provider | Abbexa |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx531366 |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Size 1 | 96 tests |
| Status | RUO |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Tested Applications | ELISA |
| UniProt ID | Q2I0M4 |
Descripcion del producto en español
Background en español
LRRC26 is a leucine-rich repeat-containing protein that functions as a regulatory subunit of large-conductance calcium-activated potassium (BK) channels, modulating their gating properties and activity. LRRC26 enhances BK channel sensitivity to calcium, allowing activation at lower intracellular calcium concentrations and contributing to processes like membrane potential regulation, ion homeostasis, and smooth muscle relaxation. It is predominantly expressed in tissues such as salivary glands, prostate, and immune cells, where it regulates fluid secretion, smooth muscle tone, and immune cell activation. LRRC26 also plays a role in modulating cell proliferation and survival, particularly in tumor cells, where it promotes BK channel activity to support cell cycle progression and growth. Dysregulation of LRRC26 has been linked to cancer progression, particularly in prostate and breast cancer, where it enhances potassium efflux and supports cell proliferation and migration. Functional studies reveal its importance in fine-tuning BK channel activity, maintaining ionic balance, and regulating cellular excitability under physiological and pathological conditions.
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