Human Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx388266
tested applications
ELISA
Description
Human Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | < 0.38 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9HBX8 |
| Gene ID | 59352 |
| OMIM | 606653 |
| Alias | LGR6,VTS20631,leucine-rich repeat-containing G protein-coupled receptor 6,leucine-rich repeat containing G protein-coupled receptor 6 |
| Background | Elisa kits for LGR6 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LGR6 is another member of the LGR receptor family that functions as a receptor for R-spondins, regulating Wnt signaling. Similar to LGR4 and LGR5, LGR6 is involved in the regulation of stem cell biology, particularly in the hair follicle and skin regeneration. LGR6 plays a role in promoting epithelial differentiation and influencing the development of various tissues during embryogenesis. It is involved in signaling pathways that maintain stem cell populations in tissues such as the skin and the gastrointestinal tract, contributing to tissue homeostasis and repair. LGR6’s expression in hair follicle stem cells suggests a role in hair growth and regeneration. Dysregulation of LGR6 has been linked to skin disorders, and its involvement in Wnt signaling makes it an important player in cancer biology. Targeting LGR6 with therapeutic agents could hold potential in treating diseases related to stem cell dysregulation, including certain types of cancer and skin regeneration disorders.
Related Products
LGR6 antibody
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Ver Producto
Recombinant Human LGR6
Ver Producto
Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6) Antibody
LGR6 Antibody is a Rabbit Polyclonal Antibody against LGR6.
Ver Producto