Human Junctional Adhesion Molecule 1 / JAM1 (F11R) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
662.5€ (96 tests)
Elisa Kits F11R
proveedor
Abbexareference
abx152073Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Junctional Adhesion Molecule 1 (JAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Junctional Adhesion Molecule 1 (JAM1) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Junctional Adhesion Molecule 1 (JAM1)No significant cross-reactivity or interference between Junctional Adhesion Molecule 1 (JAM1) and analogues was observed.
Background
The F11 receptor (F11R), also known as Junctional Adhesion Molecule-A (JAM-A), is an integral protein involved in cell-cell adhesion, particularly in the tight junctions of epithelial and endothelial cells. It belongs to the immunoglobulin superfamily and is vital for maintaining barrier integrity in tissues where selective permeability is essential, such as blood-brain, blood-testis, and blood-retina barriers. F11R plays a key role in regulating paracellular permeability, leukocyte transmigration, and cellular signaling, supporting immune responses, hemostasis, and wound healing. It also mediates interactions between platelets, contributing to thrombus formation and platelet aggregation. Expressed in a variety of tissues, including the endothelium, epithelium, and on platelets, F11R facilitates cell adhesion and communication in multiple physiological processes. Notably, it has been implicated in pathological conditions like inflammation, atherosclerosis, and cancer metastasis, where its dysregulation disrupts cellular integrity and promotes disease progression.
Características del producto
category
ELISA Kits
immunogen target
Junctional Adhesion Molecule 1 / JAM1 (F11R)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.13 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Junctional adhesion molecule A,JAM,KAT,JAM1,JAMA,JCAM,CD321,PAM-1,Junctional adhesion molecule 1,Platelet F11 receptor
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
F11R
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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