Human Interleukin 6 (IL6) Peptide

Este producto es parte de IL6 - Interleukin 6
Human Interleukin 6 (IL6) Peptide

Pida mas información

935106861

info@markelab.com

Precio

325€ (1 mg)

Protein IL6

proveedor

Abbexa

reference

abx265106

Tested Applications

reactivity

status

RUO

clonality

Descripción

IL-6 (88-121) is a peptide.


Background

IL6 is a pleiotropic cytokine involved in regulating immune responses, inflammation, and hematopoiesis It is produced by macrophages, T cells, fibroblasts, and endothelial cells in response to infections, trauma, or tissue damage IL6 activates downstream signaling through its receptor, IL-6R, and the JAK/STAT3 pathway, driving acute-phase protein synthesis, such as CRP and fibrinogen, and promoting B cell differentiation into plasma cells Dysregulated IL6 expression is associated with chronic inflammation, autoimmune diseases like rheumatoid arthritis, and cancer progression, where it promotes tumor growth, survival, and angiogenesis IL6 also contributes to cytokine storm syndrome in conditions like COVID-19, where excessive IL6 leads to hyperinflammation and organ damage Targeting IL6 signaling with anti-IL6 therapies, such as tocilizumab, has shown efficacy in treating autoimmune diseases and cytokine-driven conditions

Características del producto

category

Proteins and Peptides


origin

Human


immunogen target

Interleukin 6 (IL6)


conjugation

Unconjugated


form

Lyophilized


size 1

1 mg


size 2

5 mg


size 3

10 mg


observerd MW

Molecular Weight: 4023.57 Da Sequence Fragment: 88-121 AA


purity

> 95% (HPLC)


buffer

Not applicable.


storage

Store dry at -20 °C. Avoid repeated freeze/thaw cycles.


or code

IL6


dry ice

No


availability

Shipped within 10-20 working days.


alias

IL-6,BSF,HGF,HSF,IFNB2,CDF,B-cell stimulatory factor 2


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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