Human Interleukin 4 (IL4) Protein

Este producto es parte de IL4 - interleukin 4
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585€ (50 µg)

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935106861
info@markelab.com
name
Human Interleukin 4 (IL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651528
tested applications
WB, SDS-PAGE

Description

Interleukin 4 (IL4) Protein is a Human protein produced in 293F cell.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 4 (IL4)
Host
293F cell
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 16.6 kDa  Observed MW: 20 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: His25-Ser153
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P05112
Alias
BSF1,IL-4,BCGF1,BSF-1,BCGF-1,B-cell stimulatory factor 1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra
Background
Protein IL4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin-4 (IL4) is a crucial cytokine in the immune system, primarily involved in the regulation of humoral (antibody-mediated) immune responses and the differentiation of immune cells. It is produced by several immune cells, including activated CD4+ T cells (specifically Th2 cells), mast cells, basophils, eosinophils, and, to a lesser extent, CD8+ T cells. IL-4 is a member of the interleukin family of cytokines and plays a key role in driving the differentiation of naïve helper T cells (Th0) into Th2 cells, which are central to the adaptive immune response. This cytokine is also vital in inducing B cell class switching to immunoglobulin E (IgE), a process essential for allergic reactions. In addition to its immune-regulatory functions, IL-4 is heavily involved in allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis. IL-4 mediates a wide range of biological effects that contribute to inflammation, allergy, and immune system modulation.

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