Human Interleukin 24 (IL24) Protein

Este producto es parte de IL24 - interleukin 24
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481€ (50 µg)

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935106861
info@markelab.com
name
Human Interleukin 24 (IL24) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651391
tested applications
WB, SDS-PAGE

Description

Interleukin 24 (IL24) Protein (Active) is an active protein from Human.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 24 (IL24)
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 19.5 kDa  Observed MW: 18 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Gly51-Leu206
Tag: N-terminal His tag
Purity
> 90%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13007
Alias
C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein
Background
Protein IL24
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ

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