Human Interferon Alpha 5 (IFNa5) Protein

Este producto es parte de IFNA5 - interferon alpha 5
Human Interferon Alpha 5 (IFNa5) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein IFNA5

proveedor

Abbexa

reference

abx167164

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Interferon Alpha 5 Protein is a recombinant Human protein expressed in E. coli.


Background

Interferon Alpha 5 (IFNA5) is a member of the type I interferon family and plays a vital role in innate and adaptive immune responses. IFNA5 is secreted by immune cells like dendritic cells, macrophages, and lymphocytes in response to viral infections, double-stranded RNA, or other pathogen-associated molecular patterns (PAMPs). Once released, IFNA5 binds to the interferon-alpha/beta receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This cascade induces the transcription of interferon-stimulated genes, which activate antiviral, antiproliferative, and immunomodulatory mechanisms. These effects include inhibition of viral replication, increased antigen presentation, and activation of natural killer (NK) cells and cytotoxic T lymphocytes. While not as widely studied as IFNA2, IFNA5 may have tissue-specific or pathogen-specific roles, contributing to its nuanced function within the immune system.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Interferon Alpha 5 (IFNa5)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 52.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu22-Glu189 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IFNA5


dry ice

No


availability

Shipped within 5-7 working days.


alias

INA5,INFA5,leIF G,IFN-alphaG,IFN-alpha-5,Interferon alpha-61,Interferon alpha-G


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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