Human Interferon alpha-5 (IFNA5) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for IFNA5
proveedor
Abbexareference
abx528087Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Interferon alpha-5 (IFNA5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Interferon alpha-5 (IFNA5) concentrations in serum, plasma and other biological fluids.
Background
Interferon Alpha 5 (IFNA5) is a member of the type I interferon family and plays a vital role in innate and adaptive immune responses. IFNA5 is secreted by immune cells like dendritic cells, macrophages, and lymphocytes in response to viral infections, double-stranded RNA, or other pathogen-associated molecular patterns (PAMPs). Once released, IFNA5 binds to the interferon-alpha/beta receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This cascade induces the transcription of interferon-stimulated genes, which activate antiviral, antiproliferative, and immunomodulatory mechanisms. These effects include inhibition of viral replication, increased antigen presentation, and activation of natural killer (NK) cells and cytotoxic T lymphocytes. While not as widely studied as IFNA2, IFNA5 may have tissue-specific or pathogen-specific roles, contributing to its nuanced function within the immune system.
Características del producto
category
ELISA Kits
immunogen target
Interferon alpha-5 (IFNA5)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
INA5,INFA5,leIF G,IFN-alphaG,IFN-alpha-5,Interferon alpha-61,Interferon alpha-G
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
IFNA5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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