Human Interferon alpha-5 (IFNA5) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Human Interferon alpha-5 (IFNA5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528087
tested applications
ELISA
Description
Human Interferon alpha-5 (IFNA5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Interferon alpha-5 (IFNA5) concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | Interferon alpha-5 (IFNA5) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | P01569 |
Gene ID | 3442 |
OMIM | 147565 |
Alias | INA5,INFA5,leIF G,IFN-alphaG,IFN-alpha-5,Interferon alpha-61,Interferon alpha-G |
Background | Elisa kits for IFNA5 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Interferon Alpha 5 (IFNA5) is a member of the type I interferon family and plays a vital role in innate and adaptive immune responses. IFNA5 is secreted by immune cells like dendritic cells, macrophages, and lymphocytes in response to viral infections, double-stranded RNA, or other pathogen-associated molecular patterns (PAMPs). Once released, IFNA5 binds to the interferon-alpha/beta receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This cascade induces the transcription of interferon-stimulated genes, which activate antiviral, antiproliferative, and immunomodulatory mechanisms. These effects include inhibition of viral replication, increased antigen presentation, and activation of natural killer (NK) cells and cytotoxic T lymphocytes. While not as widely studied as IFNA2, IFNA5 may have tissue-specific or pathogen-specific roles, contributing to its nuanced function within the immune system.
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