Human Intelectin 2 (ITLN2) ELISA Kit

Este producto es parte de ITLN - Intelectin (Omentin)
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611€ (96 tests)

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935106861
info@markelab.com
name
Human Intelectin 2 (ITLN2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx252683
tested applications
ELISA

Description

Human Intelectin 2 (ITLN2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ITLN2 concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetIntelectin 2 (ITLN2)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range6.25 ng/ml - 400 ng/ml
Sensitivity3.75 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ8WWU7
Gene ID142683
OMIM609874
AliasHL2,HL-2
BackgroundElisa kits for ITLN2
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ITLN2 is a closely related intelectin family protein sharing structural and functional similarities with ITLN1 It is secreted and primarily expressed in the gastrointestinal tract and other epithelial tissues ITLN2 participates in innate immunity by recognizing and binding to microbial components, particularly carbohydrate moieties on pathogenic bacteria and fungi It enhances microbial clearance by facilitating phagocytosis and immune activation ITLN2 expression is regulated during infection and inflammation, playing a critical role in host defense mechanisms Unlike ITLN1, ITLN2 appears to have a more restricted expression pattern and is less associated with metabolic regulation, focusing on immune surveillance in mucosal surfaces Dysregulation of ITLN2 may impair barrier immunity and has been implicated in gut inflammation and intestinal disorders, where its deficiency could increase susceptibility to infections and inflammatory bowel diseases ITLN2 represents a valuable component of epithelial defense mechanisms against microbial challenges

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