Human Insulin-like Growth Factor I (IGF-I) ELISA
510€ (96 det.)
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name
Human Insulin-like Growth Factor I (IGF-I) ELISA
category
ELISA Kits
provider
Mediagnost
reference
E20
tested applications
Elisa
Description
The ELISA E20 is intended to be used for the measurement of human IGF-I in serum and plasma samples. In combination with growth retardation and other clinical symptoms the results of this test system can be used as supplementary data to assess disturbances of the growth hormone axis
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Assay Data | Reference Material: WHO 02/254 Incubation Period: 1.75 h Calibrator: rec. IGF-I Controls: 2 Controls, freeze-dried |
| Assay Type | Sandwich |
| Test Range | 0.09 – 1050 µg/L |
| Sensitivity | 0.09 µg/L |
| Recommended Dilution | 1:21 |
| Origin | Antibody: Mouse / Goat |
| Size 1 | 96 det. |
| Tested Applications | Elisa |
| Sample Type | Serum EDTA / Heparin Plasma |
| Availability | 3-5 days. |
| Storage | Shelf life: between 1 and 2 years Store the kit at 2-8°C after receipt until its expiry date |
| Alias | somatomedin C, Sm-C |
| Background | Elisa Kits for: IGF1 |
| Status | IVD |
| Note | Intra/Interassay Variance [%]< 10 |
Descripción
El Kit E20 está diseñado para la medición del IGF-I humano en muestras de suero y plasma. En combinación con el retraso del crecimiento y otros síntomas clínicos, los resultados de este sistema de prueba pueden utilizarse como datos complementarios para evaluar alteraciones del eje de la hormona del crecimiento.
Insulin-like growth factors (IGF) I and II play a pivotal role in regulating the proliferation, differentiation and specific functions of many cell types. IGF-I is identical with Somatomedin C (Sm-C) and has a molecular weight of 7649 Dalton. Its major regulators are growth hormone (GH) and nutrition, although its production in specific tissues is affected by a multitude of tropic hormones and other peptide growth factors. In contrast to many other peptide hormones, IGFs are avidly bound to specific binding proteins (IGFBP). The seven classes of IGFBPs which are known at present either bind IGF-I and IGF-II with similar affinities or show a preference for IGF-II. A major problem of IGF-I measurement results from the interference of IGFBPs in the assay. To avoid these difficulties, an uncomplicated assay was developed, in which special sample preparation is not required before measurement.
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