Human Importin subunit alpha-8 (KPNA7) ELISA Kit

Name: Human Importin subunit alpha-8 (KPNA7) ELISA Kit
Brand: Abbexa
SKU: abx528305
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de KPNA - karyopherin subunit alpha

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for KPNA7

proveedor

Abbexa

reference

abx528305

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Importin subunit alpha-8 (KPNA7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Importin subunit alpha-8 (KPNA7) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

KPNA7, or importin-α7, is the newest member of the karyopherin-α family, functioning as an adaptor protein in classical nuclear import pathways. It binds to nuclear localization signals (NLS) on cargo proteins and forms a complex with importin-β1 for transport through the nuclear pore complex (NPC). KPNA7 is expressed predominantly during early embryonic development and in germ cells, where it plays a key role in nuclear protein transport critical for zygotic genome activation and cellular differentiation. It has been implicated in embryonic development, stem cell function, and fertility. Dysregulation of KPNA7 is associated with developmental abnormalities, infertility, and certain cancers, particularly in the context of disrupted nuclear transport of transcription factors and regulatory proteins. Knockout studies suggest its essential role in early embryogenesis and nuclear transport during critical stages of development.

Características del producto

immunogen target

Importin subunit alpha-8 (KPNA7)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

IPOA8; OZEMA17,Importin subunit alpha-8

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

KPNA7

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/A9QM74

gene id

https://www.ncbi.nlm.nih.gov/gene/402569

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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