Human Importin subunit alpha-8 (KPNA7) ELISA Kit

Este producto es parte de KPNA - karyopherin subunit alpha
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Importin subunit alpha-8 (KPNA7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528305
tested applications
ELISA

Description

Human Importin subunit alpha-8 (KPNA7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Importin subunit alpha-8 (KPNA7) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Importin subunit alpha-8 (KPNA7)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
A9QM74
Gene ID
402569
OMIM
614107
Alias
IPOA8; OZEMA17,Importin subunit alpha-8
Background
Elisa kits for KPNA7
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

KPNA7, or importin-α7, is the newest member of the karyopherin-α family, functioning as an adaptor protein in classical nuclear import pathways. It binds to nuclear localization signals (NLS) on cargo proteins and forms a complex with importin-β1 for transport through the nuclear pore complex (NPC). KPNA7 is expressed predominantly during early embryonic development and in germ cells, where it plays a key role in nuclear protein transport critical for zygotic genome activation and cellular differentiation. It has been implicated in embryonic development, stem cell function, and fertility. Dysregulation of KPNA7 is associated with developmental abnormalities, infertility, and certain cancers, particularly in the context of disrupted nuclear transport of transcription factors and regulatory proteins. Knockout studies suggest its essential role in early embryogenesis and nuclear transport during critical stages of development.
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