Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528769
tested applications
ELISA
Description
Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6UXK2 |
| OMIM | 614179 |
| Alias | LINX,Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein |
| Background | Elisa kits for ISLR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ISLR2, also known as LIG-1, is a transmembrane protein characterized by Ig-like domains and LRR regions that mediate cell adhesion and signal transduction. ISLR2 is predominantly expressed in the nervous system, particularly in developing neurons, where it regulates axon guidance, neuronal migration, and synaptic plasticity. Functionally, ISLR2 acts as a cell adhesion molecule (CAM) and participates in establishing proper neuronal connectivity by interacting with other CAMs and ECM proteins. It is essential for neurodevelopment, and its dysregulation has been associated with neurodevelopmental disorders, such as autism spectrum disorders (ASD) and schizophrenia. Recent research also suggests a role in tumorigenesis, particularly in regulating the invasive properties of cancer cells.
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