Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) ELISA Kit

Este producto es parte de ISLR - immunoglobulin superfamily containing leucine rich repeat
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528769
tested applications
ELISA

Description

Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6UXK2
OMIM
614179
Alias
LINX,Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein
Background
Elisa kits for ISLR2
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ISLR2, also known as LIG-1, is a transmembrane protein characterized by Ig-like domains and LRR regions that mediate cell adhesion and signal transduction. ISLR2 is predominantly expressed in the nervous system, particularly in developing neurons, where it regulates axon guidance, neuronal migration, and synaptic plasticity. Functionally, ISLR2 acts as a cell adhesion molecule (CAM) and participates in establishing proper neuronal connectivity by interacting with other CAMs and ECM proteins. It is essential for neurodevelopment, and its dysregulation has been associated with neurodevelopmental disorders, such as autism spectrum disorders (ASD) and schizophrenia. Recent research also suggests a role in tumorigenesis, particularly in regulating the invasive properties of cancer cells.
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