Human Cis-Aconitate Decarboxylase (ACOD1) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Cis-Aconitate Decarboxylase (ACOD1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528644
tested applications
ELISA
Description
Human Cis-Aconitate Decarboxylase (ACOD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cis-Aconitate Decarboxylase (ACOD1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cis-Aconitate Decarboxylase (ACOD1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 25.5 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | A6NK06 |
| Gene ID | 730249 |
| OMIM | 615275 |
| Alias | CAD,IRG1,Immune-responsive gene 1 protein |
| Background | Elisa kits for ACOD1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Cis-aconitate decarboxylase (ACOD1), also known as immune-responsive gene 1 (IRG1), is an enzyme that converts cis-aconitate, an intermediate of the TCA cycle, into itaconate. Itaconate is a key immunometabolite with anti-inflammatory and antimicrobial properties, as it modulates cellular metabolism and inhibits the activity of pro-inflammatory enzymes like succinate dehydrogenase. ACOD1 is highly expressed in macrophages and other immune cells in response to inflammatory signals, such as lipopolysaccharide (LPS), playing a critical role in the metabolic reprogramming of immune responses. Dysregulation of ACOD1 has been implicated in inflammatory diseases and infections, with itaconate production acting as a protective mechanism against oxidative stress and pathogen growth. Its therapeutic potential is being investigated for modulating inflammation and treating immune-related disorders.
Related Products
Cis-Aconitate Decarboxylase (ACOD1) Antibody
Cis-Aconitate Decarboxylase (ACOD1) Antibody is a Rabbit Polyclonal against Cis-Aconitate Decarboxylase (ACOD1).
Ver ProductoCis-Aconitate Decarboxylase (ACOD1) Antibody (HRP)
Cis-Aconitate Decarboxylase (ACOD1) Antibody (HRP) is a Rabbit Polyclonal against Cis-Aconitate Decarboxylase (ACOD1) conjugated to HRP.
Ver Producto
Cis-Aconitate Decarboxylase (ACOD1) Antibody (FITC)
Cis-Aconitate Decarboxylase (ACOD1) Antibody (FITC) is a Rabbit Polyclonal against Cis-Aconitate Decarboxylase (ACOD1) conjugated to FITC.
Ver Producto