Human IKZF1 (DNA-binding protein Ikaros) ELISA Kit
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Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q13422 |
| Alias | DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1, IKZF1, IK1, IKAROS, LYF1, ZNFN1A1 |
| Background | Elisa kits for IKZF1 |
| Status | RUO |
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Human IKZF1 (DNA-binding protein Ikaros) ELISA Kit
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IKZF1 antibody
Transcription regulator of hematopoietic cell differentiation(PubMed:17934067). Binds gamma-satellite DNA(PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B-and T-cells. Binds and activates the enhancer(delta-A element) of the CD3-delta gene. Repressor of the TDT(fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF(SWI/SNF), in a single complex(PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells(RPCs)(By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms(PubMed:17135265, PubMed:17934067).
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