Human GP145-TrkC (TrkC) Protein (Active)

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
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1079€ (100 µg)

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935106861
info@markelab.com
name
Human GP145-TrkC (TrkC) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692619
tested applications
SDS-PAGE

Description

Human TrkC Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the extracellular domain (Met1-Asp428) of human TrkC (NP_001007157.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
TrkC
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: 72.5 kDa
Sequence Fragment: Met1-Asp428
Tag: C-terminal His tag and Fc tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 98% (SDS-PAGE)
Size 1
100 µg
Form
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NP_001007157.1
Alias
TRKC,GP145-TrkC,gp145(trkC),TrkC tyrosine kinase,Neurotrophic tyrosine kinase receptor type 3,NT-3 growth factor receptor
Background
Protein NTRK3
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Neurotrophic receptor tyrosine kinase 3 (NTRK3), also known as TrkC, binds primarily with neurotrophin-3 (NT-3) and is integral to the proper development and function of both the central and peripheral nervous systems. This receptor promotes neuronal survival, axonal growth, and the guidance of neuronal connections during development. Dysfunctions in NTRK3 signaling pathways are linked to developmental disorders, including autism spectrum disorders and some cancers, such as medulloblastomas. Its role in neurodevelopment and oncology continues to be a focus of significant clinical research.
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