Human Glycophorin-B (GYPB) ELISA Kit

Este producto es parte de GYPB - glycophorin B
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Glycophorin-B (GYPB) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525431
tested applications
ELISA

Description

Human Glycophorin-B (GYPB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Glycophorin-B (GYPB) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Glycophorin-B (GYPB)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.04 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P06028
Gene ID
2994
Alias
MNS blood group,SS,GPB,GYP,MNS,GYPA,PAS-3,CD235b,SS-active sialoglycoprotein,Sialoglycoprotein delta
Background
Elisa kits for GYPB
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Glycophorin B (GYPB) is a glycoprotein found on the surface of human red blood cells (RBCs), encoded by the GYPB gene. GYPB, along with its closely related counterpart Glycophorin A (GYPA), is integral to the erythrocyte membrane's structure and function and contributes to the MNS blood group system, which is important in transfusion medicine. The MNS blood group antigens, primarily expressed on GYPA and GYPB, define variations in RBC surfaces and can provoke immune responses in transfusion and transplantation contexts. The Ss antigens, present specifically on GYPB, are responsible for variations in RBC surfaces and are known for their immunogenic properties. Besides its role in the blood group system, GYPB contributes to the physical properties of RBCs and plays a role in host-pathogen interactions. The gene encoding GYPB is highly homologous to GYPA, and these two genes likely originated through gene duplication and share considerable sequence identity. GYPB's specific structural characteristics and glycosylation pattern contribute to its interactions with pathogens, making it relevant in infectious disease dynamics, especially in malaria research, given that certain Plasmodium species use glycophorins to invade RBCs.

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