Human Glycophorin-B (GYPB) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Glycophorin-B (GYPB) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525431
tested applications
ELISA
Description
Human Glycophorin-B (GYPB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Glycophorin-B (GYPB) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Glycophorin-B (GYPB) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.04 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P06028 |
| Gene ID | 2994 |
| Alias | MNS blood group,SS,GPB,GYP,MNS,GYPA,PAS-3,CD235b,SS-active sialoglycoprotein,Sialoglycoprotein delta |
| Background | Elisa kits for GYPB |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Glycophorin B (GYPB) is a glycoprotein found on the surface of human red blood cells (RBCs), encoded by the GYPB gene. GYPB, along with its closely related counterpart Glycophorin A (GYPA), is integral to the erythrocyte membrane's structure and function and contributes to the MNS blood group system, which is important in transfusion medicine. The MNS blood group antigens, primarily expressed on GYPA and GYPB, define variations in RBC surfaces and can provoke immune responses in transfusion and transplantation contexts. The Ss antigens, present specifically on GYPB, are responsible for variations in RBC surfaces and are known for their immunogenic properties. Besides its role in the blood group system, GYPB contributes to the physical properties of RBCs and plays a role in host-pathogen interactions. The gene encoding GYPB is highly homologous to GYPA, and these two genes likely originated through gene duplication and share considerable sequence identity. GYPB's specific structural characteristics and glycosylation pattern contribute to its interactions with pathogens, making it relevant in infectious disease dynamics, especially in malaria research, given that certain Plasmodium species use glycophorins to invade RBCs.
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