Human Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein
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935106861
info@markelab.com
Precio
225€ (5 µg)
Protein GAPDH
proveedor
Abbexareference
abx073506Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
GAPDH Enzyme is a recombinant enzyme.
Background
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
host
E. coli
form
Liquid
tested applications
SDS-PAGE
size 1
5 µg
size 2
20 µg
size 3
1 mg
expression
Recombinant
purity
> 95% (SDS-PAGE)
storage
Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
or code
GAPDH
dry ice
No
availability
Shipped within 5-10 working days.
alias
GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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