Human Glutathione Hydrolase 1 Proenzyme (GGT1) CLIA Kit
643.5€ (96 tests)
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935106861
info@markelab.com
name
Human Glutathione Hydrolase 1 Proenzyme (GGT1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196684
tested applications
CLIA
Description
Human Gamma Glutamyltransferase 1 (γGT1) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Gamma Glutamyltransferase 1 (γGT1).
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Glutathione Hydrolase 1 Proenzyme (GGT1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.31 ng/ml - 20 ng/ml |
| Sensitivity | 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | GGT,GTG,GGTD,CD224,GGT 1,D22S672,D22S732 |
| Background | CLIA Kits GGT1 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Gamma-Glutamyltransferase 1 (GGT1) is a membrane-bound enzyme that catalyzes the transfer of gamma-glutamyl moieties from glutathione to amino acids and peptides, playing a critical role in glutathione homeostasis and antioxidant defense GGT1 is essential for the breakdown and recycling of glutathione, a key molecule in detoxifying reactive oxygen species (ROS) and maintaining cellular redox balance GGT1 is highly expressed in the kidney, liver, and other epithelial tissues, where it regulates amino acid transport and cellular responses to oxidative stress Dysregulation of GGT1 activity is associated with oxidative damage, inflammation, and metabolic diseases, including liver disorders, cardiovascular disease, and diabetes Elevated GGT1 levels are also observed in cancers such as hepatocellular carcinoma and lung cancer, where they promote tumor progression and chemoresistance through enhanced glutathione metabolism Additionally, GGT1 serves as a biomarker for liver function and oxidative stress-related conditions Its role in glutathione metabolism and cellular redox regulation underscores its importance in maintaining cellular health and defense mechanisms
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