Human Glutamate Decarboxylase 2 (GAD2) Protein

Product Graph
221€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Glutamate Decarboxylase 2 (GAD2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652154
tested applications
WB, SDS-PAGE

Description

Glutamate Decarboxylase 2 (GAD2) Protein is a Recombinant protein from Human. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Glutamate Decarboxylase 2 (GAD2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 21.6 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Met188-Ser374
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q05329
Background
Protein GAD2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Related Products

EH0732

Human GAD2 (Glutamate decarboxylase 2) ELISA Kit

Ver Producto
EM2529

Mouse GAD2 (Glutamate Decarboxylase 2, Acid) ELISA Kit

Ver Producto
ER0969

Rat GAD2 (Glutamate Decarboxylase 2, Acid) ELISA Kit

Ver Producto