Glutamate Decarboxylase 2 (GAD2) Antibody
383.5€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Glutamate Decarboxylase 2 (GAD2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx016167
Tested Applications
ELISA, FCM
Description
Glutamate Decarboxylase 2 (GAD2) Antibody is a Mouse Monoclonal against Glutamate Decarboxylase 2 (GAD2). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Glutamate Decarboxylase 2 (GAD2) Immunogen: Purified recombinant fragment of human GAD2 (AA: 1-100) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 65.4 kDa |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q05329 |
| Gene ID | 2572 |
| NCBI Accession | NM_000818.2, NM_001134366.1 |
| OMIM | 138275 |
| Background | Antibody anti-GAD2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
Glutamate Decarboxylase 2 (GAD2) Antibody
Glutamate Decarboxylase 2 (GAD2) Antibody is a Rabbit Polyclonal antibody against Glutamate Decarboxylase 2 (GAD2). This…
Ver producto Glutamate Decarboxylase 2 (GAD2) Antibody
Glutamate Decarboxylase 2 (GAD2) Antibody is a Mouse Monoclonal against Glutamate Decarboxylase 2 (GAD2). This gene enco…
Ver producto
Glutamate Decarboxylase 2 (GAD2) Antibody
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-depe…
Ver producto