Glutamate Decarboxylase 2 (GAD2) Antibody
559€ (100 µl)
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Name
Glutamate Decarboxylase 2 (GAD2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx025417
Tested Applications
ELISA, WB
Description
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. This antibody is supplied as crude ascites.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Glutamate Decarboxylase 2 (GAD2) Immunogen: KLH-conjugated synthetic peptide between 109-138 amino acids from human GAD2. |
| Host | Mouse |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/100 - 1/1600. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | Calculated MW: 65.4 kDa |
| Purification | Unpurified crude ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q05329, Q05683 |
| Gene ID | 2572, 24380 |
| OMIM | 138275 |
| Background | Antibody anti-GAD2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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