Human GDF15 (Growth Differentiation Factor 15) ELISA Kit

Este producto es parte de GDF15 - Growth Differentiation Factor 15
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935106861
info@markelab.com
name
Human GDF15 (Growth Differentiation Factor 15) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH0150
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
23.438-1500pg/ml
Sensitivity
14.063pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q99988
Alias
HG,PDF,MIC1;,PLAB,MIC-1,NAG-1,PTGFB, GDF-15
Background
Elisa kits for GDF15
Status
RUO

GDF15, a stress-responsive cytokine, stands as a distinct member within the diverse TGF-β superfamily. Its expression is typically low in most tissues during normal physiological conditions. However, when cardiac myocytes face ischemia or heightened ventricular wall stress, GDF-15 expression intensifies significantly. This cytokine has emerged as a potent prognostic indicator in various diseases, including heart diseases and cancer. Interestingly, it appears to act protectively against cardiac injury, attributed to its antihypertrophic, antiapoptotic, and anti-inflammatory properties, although the specific receptor through which GDF-15 exerts its effects remains unidentified. Studies have revealed a positive correlation between elevated GDF-15 levels and factors such as LV mass, IL-6, and MMP-9 levels in patients with heart failure (HF)

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