Human Adhesion G Protein-Coupled Receptor V1 (ADGRV1) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ADGRV1
proveedor
Abbexareference
abx526077Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human G-protein coupled receptor 98 (ADGRV1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human G-protein coupled receptor 98 (ADGRV1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Adhesion G-protein coupled receptor V1 (ADGRV1), also known as GPR98, is a member of the adhesion GPCR family. ADGRV1 is a large transmembrane protein with an extracellular domain containing multiple adhesion motifs, a seven-transmembrane domain characteristic of G protein-coupled receptors (GPCRs), and an intracellular domain involved in signaling. ADGRV1 is primarily expressed in the inner ear and is essential for auditory function. It plays a crucial role in the development and maintenance of stereocilia, the specialized hair-like structures in the inner ear that detect sound vibrations and convert them into electrical signals. Mutations in the ADGRV1 gene are associated with various forms of hereditary hearing loss, including Usher syndrome type IIC and nonsyndromic deafness. These mutations disrupt the normal function of ADGRV1, leading to structural abnormalities in the stereocilia or impairment of signal transduction in the inner ear.
Características del producto
category
ELISA Kits
immunogen target
Adhesion G Protein-Coupled Receptor V1 (ADGRV1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ADGRV1,FEB4 GPR98,MASS1,USH2B,USH2C,VLGR1,VLGR1b
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ADGRV1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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