935106861
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Precio
525€ (96 tests)
Human G Protein Coupled Receptor 37 (GPR37) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GPR37 concentrations in tissue homogenates, cell lysates and other biological fluids.
GPR37, also known as the parkin receptor, is a G protein-coupled receptor expressed primarily in the brain, particularly in dopaminergic neurons. GPR37 plays an important role in regulating neuronal signaling, synaptic plasticity, and neuroinflammation. It is activated by its endogenous ligand, which remains largely unidentified, and couples to Gi proteins, leading to the inhibition of adenylate cyclase and modulation of other intracellular signaling pathways. GPR37 is involved in the pathophysiology of Parkinson's disease, as it is associated with the parkin gene, which is implicated in the degeneration of dopaminergic neurons. Mutations in the GPR37 gene have been linked to various neurodegenerative diseases, making this receptor an interesting target for therapeutic research. The receptor's potential as a modulator of neuroinflammation and neuronal survival is being explored for new treatments aimed at neurodegenerative diseases such as Parkinson’s.
ELISA Kits
G Protein Coupled Receptor 37 (GPR37)
Human
0.156 ng/ml - 10 ng/ml
0.1 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
GPR37,EDNRBL,EDNRLB,PAELR,G-protein coupled receptor CNS1,parkin-associated endothelin B-like receptor,Endothelin B receptor-like protein 1,hET(B)R-LP
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
GPR37
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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