Human Fructose-Bisphosphate Aldolase A (ALDOA) Protein

Este producto es parte de ALDOA - Fructose-Bisphosphate Aldolase A
Human Fructose-Bisphosphate Aldolase A (ALDOA) Protein
221€ (10 µg)

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Name
Human Fructose-Bisphosphate Aldolase A (ALDOA) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx065218
Tested Applications
WB, SDS-PAGE

Description

Human Aldolase A, Fructose Bisphosphate (ALDOA) is a recombinant Human protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Fructose-Bisphosphate Aldolase A (ALDOA)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Asp18-Gly273
Tag: N-terminal His tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 31.6 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P04075
Gene ID
226
OMIM
103850
Alias
ALDOA,ALDA
Background
Protein ALDOA
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate during glycolysis. It is widely expressed, particularly in muscle tissues and the brain, where it plays a crucial role in energy metabolism and ATP production. ALDOA is vital for providing energy to rapidly proliferating cells and tissues with high metabolic demands. Dysregulation of ALDOA has been associated with cancer progression, as elevated glycolytic activity (Warburg effect) fuels tumor growth. Mutations in ALDOA cause glycogen storage disease type XII, characterized by hemolytic anemia and muscle weakness due to impaired glycolytic flux. Its role in energy metabolism underscores its importance in cellular homeostasis, growth, and disease.

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