Human Frataxin, Mitochondrial (FXN) Protein
312€ (20 µg)
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name
Human Frataxin, Mitochondrial (FXN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694142
tested applications
SDS-PAGE
Description
Human Frataxin, Mitochondrial (FXN) Protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: Calculated MW: 18.48 kDa Observed MW (SDS-PAGE): 21 kDa Sequence Fragment: Leu42-Ala210 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | >95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute in sterile H2O. Do not vortex. |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store lyophilized between -20 °C and -80 °C. |
| Dry Ice | No |
| UniProt ID | Q16595 |
| OMIM | 2293 |
| Background | Protein FXN |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Human FXN (Frataxi) ELISA Kit
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FXN antibody
FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.
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