FXN antibody
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name
FXN antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03255
tested applications
ELISA, WB
Description
FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | frataxin (FXN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 14 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q16595 |
| Gene ID | 2395 |
| Alias | Frataxin, mitochondrial,Friedreich ataxia protein (Fxn),Frataxin intermediate form (i-FXN),Frataxin(56-210) Alternative names: m56-FXN,Frataxin(78-210) Alternative names: d-FXN,m78-FXN,Frataxin mature form Alternative names: Frataxin(81-210),m81-FXN,Extramitochondrial frataxin,FXN,FRDA,X25 |
| Background | Antibody anti-FXN |
| Status | RUO |
| Note | Mol. Weight 14 kDa |
Descripción
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Human FXN (Frataxi) ELISA Kit
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FXN antibody
FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.
Ver Producto