Recombinant Human FXN

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935106861
info@markelab.com
name
Recombinant Human FXN
category
Proteins and Peptides
provider
FineTest
reference
P5876
tested applications
Western Blot, ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Host | E.Coli |
Reactivity | Human |
Assay Data | Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex. |
Recommended Dilution | ¥ |
Isotype | ¥ |
Clone ID | ¥ |
Observed MW | 16.9 kDa |
Expression | 56-210 |
Purity | Greater than 90% as determined by SDS-PAGE. |
Size 1 | 50μg |
Size 2 | 200μg |
Size 3 | 1mg |
Form | Lyophilized powder |
Tested Applications | Western Blot, ELISA |
Buffer | Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4. |
Availability | 7 days |
Storage | The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle. |
UniProt ID | Q16595 |
Alias | CyaY, d-FXN, FA, FARR, Frataxin mature form, Frataxin(81-210), FRDA, FRDA_HUMAN, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, MGC57199, X25 |
Background | Protein FXN |
Status | RUO |
Note | Tag : N-terminal His Tag |
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FXN antibody
FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.
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