Human Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
531.25€ (96 tests)
Elisa Kits FCGR3A
proveedor
Abbexareference
abx252443Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
FCGR3A, or Fc gamma receptor IIIa, is a membrane-bound protein that plays a crucial role in the immune system, specifically in mediating immune responses through the recognition of the Fc region of IgG antibodies. This receptor is primarily expressed on the surface of natural killer (NK) cells, macrophages, monocytes, and dendritic cells, where it facilitates antibody-dependent cellular cytotoxicity (ADCC) and other immune responses. It is part of the broader family of Fc gamma receptors (FcγRs), which are responsible for binding to the Fc region of IgG antibodies, thereby linking humoral and cellular immunity. FCGR3A has garnered considerable attention in immunology due to its role in recognizing and responding to immune complexes, infected cells, and tumor cells coated with IgG antibodies. Variations in the gene encoding FCGR3A have been implicated in differential responses to infections, autoimmune diseases, and cancer therapies
Características del producto
category
ELISA Kits
immunogen target
Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A)
reactivity
Human
test range
7.81 ng/ml - 500 ng/ml
sensitivity
4.69 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CD16,FCG3,CD16A,FCGR3,IGFR3,IMD20,FCR-10,FCRIII,CD16-II,FCGRIII,FCRIIIA,FcGRIIIA,Low affinity immunoglobulin gamma Fc region receptor III-A,IgG Fc receptor III-A,IgG Fc receptor III-2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FCGR3A
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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