Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx521999
tested applications
ELISA
Description
Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9UHX3 |
| Alias | ADGRE2,EMR2,EGF-like module-containing mucin-like hormone receptor-like 2,CD312 |
| Background | Elisa kits for ADGRE2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADGRE2, or EMR2, is an adhesion GPCR expressed on myeloid cells, including monocytes, macrophages, and eosinophils, where it modulates immune responses and cellular adhesion. Its structure includes multiple extracellular EGF-like domains that enable interactions with ligands and the extracellular matrix. ADGRE2 is involved in processes such as cell migration, adhesion, and activation during inflammatory and immune responses. Mutations in ADGRE2 have been linked to vibratory urticaria, a rare inherited disorder characterized by hives triggered by mechanical vibrations, suggesting its role in mechanosensation and immune cell activation. The receptor’s involvement in eosinophil-mediated responses also points to potential roles in allergic diseases and eosinophilic inflammation.
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