Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ADGRE2
proveedor
Abbexareference
abx521999Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADGRE2, or EMR2, is an adhesion GPCR expressed on myeloid cells, including monocytes, macrophages, and eosinophils, where it modulates immune responses and cellular adhesion. Its structure includes multiple extracellular EGF-like domains that enable interactions with ligands and the extracellular matrix. ADGRE2 is involved in processes such as cell migration, adhesion, and activation during inflammatory and immune responses. Mutations in ADGRE2 have been linked to vibratory urticaria, a rare inherited disorder characterized by hives triggered by mechanical vibrations, suggesting its role in mechanosensation and immune cell activation. The receptor’s involvement in eosinophil-mediated responses also points to potential roles in allergic diseases and eosinophilic inflammation.
Características del producto
category
ELISA Kits
immunogen target
EGF-like module-containing mucin-like hormone receptor-like 2 (ADGRE2)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ADGRE2,EMR2,EGF-like module-containing mucin-like hormone receptor-like 2,CD312
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ADGRE2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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