Human EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2) Protein
195€ (10 µg)
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935106861
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name
Human EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166412
tested applications
WB, SDS-PAGE
Description
EGF Like Module Containing Mucin Like Hormone Receptor 2 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 21.4 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn347-Ser509 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UHX3 |
| Alias | ADGRE2,EMR2,EGF-like module-containing mucin-like hormone receptor-like 2,CD312 |
| Background | Protein ADGRE2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADGRE2, or EMR2, is an adhesion GPCR expressed on myeloid cells, including monocytes, macrophages, and eosinophils, where it modulates immune responses and cellular adhesion. Its structure includes multiple extracellular EGF-like domains that enable interactions with ligands and the extracellular matrix. ADGRE2 is involved in processes such as cell migration, adhesion, and activation during inflammatory and immune responses. Mutations in ADGRE2 have been linked to vibratory urticaria, a rare inherited disorder characterized by hives triggered by mechanical vibrations, suggesting its role in mechanosensation and immune cell activation. The receptor’s involvement in eosinophil-mediated responses also points to potential roles in allergic diseases and eosinophilic inflammation.
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