Human EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2) Protein

Name: Human EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2) Protein
Brand: Abbexa
SKU: abx166412
Price: 187.5 EUR
Availability: OnlineOnly

Este producto es parte de ADGRE - Adhesion G protein-coupled receptor E

Pida mas información

935106861

info@markelab.com

Precio

187.5€ (10 µg)

Protein ADGRE2

proveedor

Abbexa

reference

abx166412

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

EGF Like Module Containing Mucin Like Hormone Receptor 2 Protein is a recombinant Human protein expressed in E. coli.

Background

ADGRE2, or EMR2, is an adhesion GPCR expressed on myeloid cells, including monocytes, macrophages, and eosinophils, where it modulates immune responses and cellular adhesion. Its structure includes multiple extracellular EGF-like domains that enable interactions with ligands and the extracellular matrix. ADGRE2 is involved in processes such as cell migration, adhesion, and activation during inflammatory and immune responses. Mutations in ADGRE2 have been linked to vibratory urticaria, a rare inherited disorder characterized by hives triggered by mechanical vibrations, suggesting its role in mechanosensation and immune cell activation. The receptor’s involvement in eosinophil-mediated responses also points to potential roles in allergic diseases and eosinophilic inflammation.

Características del producto

origin

Human

host

E. coli

immunogen target

EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2)

host

E. coli

conjugation

Unconjugated

form

Lyophilized

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

1 mg

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

ADGRE2

dry ice

availability

Shipped within 5-7 working days.

alias

ADGRE2,EMR2,EGF-like module-containing mucin-like hormone receptor-like 2,CD312

uniprot id

https://www.uniprot.org/uniprotkb/Q9UHX3

note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.

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EGF Like Module Containing Mucin Like Hormone Receptor 2 (EMR2) Antibody

proveedor

Abbexa

reference

abx128952

Tested Applications

WB, IHC, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

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