Human Dynein Light Chain LC8-Type 2 (DYNLL2) ELISA Kit

Este producto es parte de DYNLL - dynein light chain LC8-type 1
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Dynein Light Chain LC8-Type 2 (DYNLL2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx387019
tested applications
ELISA

Description

Human Dynein Light Chain LC8-Type 2 (DYNLL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DYNLL2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Dynein Light Chain LC8-Type 2 (DYNLL2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.094 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q96FJ2
Gene ID
140735
OMIM
608942
Alias
DLC2,DNCL1B,Dlc2,RSPH22,8 kDa dynein light chain b,DLC8b,Dynein light chain LC8-type 2
Background
Elisa kits for DYNLL2
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Dynein light chain 2, cytoplasmic (DYNLL2) is a protein that plays a vital role in regulating the function of the dynein motor complex, a key molecular motor involved in the transport of cellular cargo along microtubules in the cytoplasm DYNLL2, as a light chain component, helps stabilize the dynein complex and is involved in intracellular processes such as vesicle trafficking, organelle positioning, and mitotic spindle formation During cell division, DYNLL2 is required for the proper organization of the mitotic spindle and the movement of chromosomes, ensuring accurate cell division Additionally, DYNLL2 is implicated in regulating the actin cytoskeleton and modulating cellular signaling pathways, such as those involved in apoptosis and stress responses Dysregulation of DYNLL2 has been linked to various diseases, including neurodegenerative disorders, where impaired intracellular transport and organelle dysfunction contribute to neuronal damage DYNLL2’s essential roles in intracellular transport, cell cycle regulation, and cellular signaling make it crucial for maintaining normal cellular function and homeostasis

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