Dynein Light Chain LC8-Type 2 (DYNLL2) Antibody
637€ (100 µl)
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935106861
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name
Dynein Light Chain LC8-Type 2 (DYNLL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx112206
tested applications
ELISA, WB
Description
Dynein, Light Chain, Lc8-Type 2 Antibody is a Rabbit Polyclonal antibody against Dynein, Light Chain, Lc8-Type 2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Dynein Light Chain LC8-Type 2 (DYNLL2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96FJ2 |
| Gene ID | 140735 |
| OMIM | 608942 |
| Alias | DLC2,DNCL1B,Dlc2,RSPH22,8 kDa dynein light chain b,DLC8b,Dynein light chain LC8-type 2 |
| Background | Antibody anti-DYNLL2 |
| Status | RUO |
Descripción
Dynein light chain 2, cytoplasmic (DYNLL2) is a protein that plays a vital role in regulating the function of the dynein motor complex, a key molecular motor involved in the transport of cellular cargo along microtubules in the cytoplasm DYNLL2, as a light chain component, helps stabilize the dynein complex and is involved in intracellular processes such as vesicle trafficking, organelle positioning, and mitotic spindle formation During cell division, DYNLL2 is required for the proper organization of the mitotic spindle and the movement of chromosomes, ensuring accurate cell division Additionally, DYNLL2 is implicated in regulating the actin cytoskeleton and modulating cellular signaling pathways, such as those involved in apoptosis and stress responses Dysregulation of DYNLL2 has been linked to various diseases, including neurodegenerative disorders, where impaired intracellular transport and organelle dysfunction contribute to neuronal damage DYNLL2’s essential roles in intracellular transport, cell cycle regulation, and cellular signaling make it crucial for maintaining normal cellular function and homeostasis
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