Human Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides (DAPP1) CLIA Kit
845€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides (DAPP1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495673
tested applications
CLIA
Description
Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides (DAPP1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.055 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | DAPP1, BAM32,B lymphocyte adapter protein Bam32 |
| Background | CLIA Kits DAPP1 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DAPP1 (Dual Adapter for Phosphotyrosine and 3-Phosphoinositide) is a multifunctional adaptor protein involved in the regulation of cellular signaling pathways. It contains both SH2 (Src Homology 2) and PH (Pleckstrin Homology) domains, which allow it to interact with phosphorylated tyrosine residues and phosphoinositides, respectively. These interactions make DAPP1 a key player in the regulation of various cellular processes, including signal transduction, immune responses, and actin cytoskeleton remodeling. DAPP1 is especially important in immune cells, where it participates in the regulation of B cell receptor (BCR) signaling. Upon BCR activation, DAPP1 translocates to the plasma membrane and helps coordinate downstream signaling events that control cell survival, differentiation, and proliferation. It plays a role in modulating cell motility and the immune synapse, contributing to efficient immune responses. DAPP1 is also involved in the regulation of intracellular calcium signaling, which is crucial for processes like cell activation and communication. Its function is tightly regulated, and alterations in DAPP1 expression or activity can lead to immune dysfunction and have been implicated in various diseases, including cancer and autoimmune disorders.
Related Products
anti- DAPP1 antibody
May act as a B-cell-associated adapter that regulates B-cell antigen receptor(BCR)-signaling downstream of PI3K.
Ver Producto
Dual Adaptor of Phosphotyrosine And 3-Phosphoinositides 1 (DAPP1) Antibody
DAPP1 may act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR) signaling downstream of PI3K.
Ver Producto
Dual Adaptor of Phosphotyrosine And 3-Phosphoinositides 1 (DAPP1) Antibody
Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides Antibody is a Rabbit Polyclonal antibody against Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides.
Ver Producto