Human Docking Protein 6 (DOK6) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DOK6
proveedor
Abbexareference
abx250617Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Docking Protein 6 (DOK6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Docking protein 6 concentrations in serum, plasma and other biological fluids.
Background
DOK6 is an adaptor protein in the DOK family that interacts with RET and other receptor tyrosine kinases, promoting neuronal development and survival. It is highly expressed in the nervous system, particularly in sensory and motor neurons, where it regulates neurite outgrowth and axonal guidance through the activation of MAPK/ERK pathways. DOK6 interacts with signaling proteins via its PTB and PH domains to mediate downstream effects. It plays a role in neurotrophic signaling, and its dysregulation is linked to impaired neural differentiation and neurodevelopmental disorders. Studies highlight its importance in promoting axonal elongation and neuronal connectivity.
Características del producto
category
ELISA Kits
immunogen target
Docking Protein 6 (DOK6)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
Downstream of tyrosine kinase 6,DOK5L
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DOK6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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