Docking Protein 6 (DOK6) Antibody
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935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-DOK6
proveedor
Abbexareference
abx013664Tested Applications
ELISA, WB, IF/ICCreactivity
Human, Mousestatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against DOK6 protein. Immunogen region is Internal.
Background
DOK6 is an adaptor protein in the DOK family that interacts with RET and other receptor tyrosine kinases, promoting neuronal development and survival. It is highly expressed in the nervous system, particularly in sensory and motor neurons, where it regulates neurite outgrowth and axonal guidance through the activation of MAPK/ERK pathways. DOK6 interacts with signaling proteins via its PTB and PH domains to mediate downstream effects. It plays a role in neurotrophic signaling, and its dysregulation is linked to impaired neural differentiation and neurodevelopmental disorders. Studies highlight its importance in promoting axonal elongation and neuronal connectivity.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse
immunogen target
Docking Protein 6 (DOK6)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IF/ICC
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
recommended dilution
WB: 1/500 - 1/3000, IF/ICC: 1/100 - 1/500, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
DOK6
dry ice
No
availability
Shipped within 5-10 working days.
alias
Downstream of tyrosine kinase 6,DOK5L
uniprot id
note
Concentration: 1 mg/ml -
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