Human Desmoyokin (AHNAK) Protein
234€ (10 µg)
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935106861
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name
Human Desmoyokin (AHNAK) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166829
tested applications
WB, SDS-PAGE
Description
Desmoyokin Protein is a Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Desmoyokin (AHNAK) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Asp300 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AHNAK1RS,PM227,AHNAK |
| Background | Protein AHNAK |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
AHNAK is a large, multifunctional nucleoprotein involved in cellular architecture, calcium signaling, and membrane repair. It is highly expressed in epithelial cells, fibroblasts, and immune cells, where it localizes to the cytoplasm, plasma membrane, and nucleus. AHNAK interacts with actin and other cytoskeletal elements, contributing to cell shape maintenance, cell migration, and membrane dynamics. It also plays a key role in calcium homeostasis by interacting with calcium channels, such as annexins and S100A10, and facilitating membrane repair processes in response to injury. AHNAK is implicated in tumor progression, particularly in cancers like glioblastoma, breast cancer, and melanoma, where its expression correlates with cell motility and invasive potential. Additionally, AHNAK has been associated with immune regulation, influencing T-cell activation and migration. Dysregulation of AHNAK contributes to cardiac hypertrophy, immune dysfunction, and cancer metastasis.
Related Products
Desmoyokin (AHNAK) Antibody
Desmoyokin (AHNAK) Antibody is a Rabbit Polyclonal against AHNAK.
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