Human Desmoyokin (AHNAK) ELISA Kit

Este producto es parte de AHNAK - AHNAK nucleoprotein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Desmoyokin (AHNAK) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx151304
tested applications
ELISA

Description

Human Desmoyokin (AHNAK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Desmoyokin (AHNAK) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Desmoyokin (AHNAK)

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Desmoyokin (AHNAK)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
AHNAK1RS,PM227,AHNAK
Background
Elisa kits for AHNAK
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

AHNAK is a large, multifunctional nucleoprotein involved in cellular architecture, calcium signaling, and membrane repair. It is highly expressed in epithelial cells, fibroblasts, and immune cells, where it localizes to the cytoplasm, plasma membrane, and nucleus. AHNAK interacts with actin and other cytoskeletal elements, contributing to cell shape maintenance, cell migration, and membrane dynamics. It also plays a key role in calcium homeostasis by interacting with calcium channels, such as annexins and S100A10, and facilitating membrane repair processes in response to injury. AHNAK is implicated in tumor progression, particularly in cancers like glioblastoma, breast cancer, and melanoma, where its expression correlates with cell motility and invasive potential. Additionally, AHNAK has been associated with immune regulation, influencing T-cell activation and migration. Dysregulation of AHNAK contributes to cardiac hypertrophy, immune dysfunction, and cancer metastasis.

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