Human Desmoyokin (AHNAK) CLIA Kit
845€ (96 tests)
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name
Human Desmoyokin (AHNAK) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495757
tested applications
CLIA
Description
Human Desmoyokin (AHNAK) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Desmoyokin (AHNAK) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.059 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AHNAK1RS,PM227,AHNAK |
| Background | CLIA Kits AHNAK |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AHNAK is a large, multifunctional nucleoprotein involved in cellular architecture, calcium signaling, and membrane repair. It is highly expressed in epithelial cells, fibroblasts, and immune cells, where it localizes to the cytoplasm, plasma membrane, and nucleus. AHNAK interacts with actin and other cytoskeletal elements, contributing to cell shape maintenance, cell migration, and membrane dynamics. It also plays a key role in calcium homeostasis by interacting with calcium channels, such as annexins and S100A10, and facilitating membrane repair processes in response to injury. AHNAK is implicated in tumor progression, particularly in cancers like glioblastoma, breast cancer, and melanoma, where its expression correlates with cell motility and invasive potential. Additionally, AHNAK has been associated with immune regulation, influencing T-cell activation and migration. Dysregulation of AHNAK contributes to cardiac hypertrophy, immune dysfunction, and cancer metastasis.
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